WebStudy design: Biomechanical, in vitro, and initial in vivo evaluation of a thiol-modified hyaluronan (TM-HA) and elastin-like polypeptide (ELP) composite hydrogel for nucleus … WebMar 1, 2004 · Two thiolated hyaluronan (HA) ... Hyaluronan (HA) is a major constituent of the extracellular matrix (ECM), and is the only non-sulfated glycosaminoglycan (GAG) [33]. This polyanionic GAG is biocompatible, and biodegradable, and performs important biological functions, such as stabilizing and organizing the ECM [34], [35], regulating cell ...
Effects of the bonding intensity between hyaluronan and gelatin …
WebThe platform of claim 1, wherein the telechelic polymer is thiolated poly (N-isopropylacrylamide) (PNIPAm). ... Toll4, RAAMM receptor or hyaluronan receptors for endocytosis. (vi) HA degraded from HA-based polymeric biomaterials may serve as a lubricant and shock absorber in the joints. HA could stabilize the joint function due to its ... WebDec 22, 2024 · In this study, maleiated sodium hyaluronate (MHA) with a high substituted degree of the acrylate group (i.e., 2.27) and thiolated sodium hyaluronate (SHHA) were synthesized. By blending these modified HAs, the MHA/SHHA hydrogels were prepared via pre-crosslinking through thiol–acrylate Michael addition and subsequently covalent … entity concept meaning
US Patent Application for Thiol-modified hyaluronan Patent …
WebJun 20, 2013 · The thiolated hyaluronan (HA-SH) was synthesized as described in the literature 41 with high molecular weight hyaluronan (Sigma-Aldrich) leading to HA-SH molecules with an average of 450 kDa. WebSummary: Fibrous and interstitial proteins compose the extracellular matrix of the vocal fold lamina propria and account for its biomechanic properties. Vocal fold scarring is characterized by altered biomechanical properties, which create dysphonia. Although alterations of the fibrous proteins have been confirmed in the rabbit vocal fold scar, … WebJan 1, 2014 · Thiolated hyaluronan (Glycosil ®, CMHA-S or carboxymethylated, thiolated hyaluronic acid), thiolated porcine gelatin (Gelin-S ®) and polyethylene glycol diacrylate … dr healy dds